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Search Results for " ccr1 antagonist 1 "

11

Compounds

Cat No. Product Name Synonyms Targets
T10708 CCR1 antagonist 6 CCR
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
T15253 CCX354 CCR1 antagonist 1,CCX-354,CCX 354 CCR
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.
T10709 CCR1 antagonist 7 CCR
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
T14899 CCR1 antagonist 8 CCR
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay).
T10710 CCR1 antagonist 9 CCR
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
T2375 BX471 BX 471,BX-471,ZK-811752 CCR
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.
T28072L MLN-3897 TFA MLN-3897 TFA(1010731-97-1 Free base) CCR
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
T14845 BX471 hydrochloride ZK-811752 hydrochloride Others
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
T28072 MLN-3897 AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897 CCR
MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.
T68427 MLN-3897 citrate
MLN-3897 citrate is a C-C Motif Chemokine Receptor 1 (CCR1) antagonist potentially for the treatment of multiple sclerosis and rheumatoid arthritis.
T73371 BAY-3153
BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .
TargetMol